Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Herein, we present a report detailing the synthesis of column chromatography-free, heterogeneous vanadium doped titanium dioxide nanoparticles (VTiO2 NPs) for catalysing the 1,6 Michael addition of 3-methyl-5-pyrazolone onto 3-methyl-4-nitro-5-alkenyl isoxazoles. Additionally, we report the swift synthesis of 3,3-di(indolyl)indolin-2-ones through the reaction of indole on isatin at room temperature in water, marking the first instance of such a process. The 1,6 Michael addition reaction yielded moderate to good yields, while the 3,3-bis(indolyl)oxindole products were obtained in quantitative yield.