The rapid growth of e-commerce as revolutionized a way businesses of operate and customers shop. However, challenges of such as of security concerns, lacks of trust, and suboptimal customer experiences persist. This research paper proposes a novel approach to address these challenges by integrating artificial intelligence (AI) and blockchain technologies into e-commerce applications. By leveraging AI for personalized recommendations, fraud detection, and chatbot assistance, and utilizing blockchain for enhanced security, transparency, and trust, this research aims to improve customer experiences and foster trust in e-commerce transactions. The paper provides an in-depth analysis of the proposed framework, its potential benefits, and the challenges that need to be addressed for successful implementation. Additionally, a case study is presented to demonstrate the practical application and effectiveness of the proposed solution. The findings highlight the immense potential of AI and blockchain integration in shaping the future of e- commerce.