Given the large degree of genetic variability and complicated aggregation, the order of autosomal recessive ataxias faces a significant challenge. As new innovations are developing for extended targeted quality testing, we conducted a thorough intentional review of the literature to look at all recessive ataxias in order to suggest another grouping and suitably embrace this field. The most well-known autosomal recessive genetic disease in the Caucasian population is cystic fibrosis. Expanding knowledge about sub-atomic pathology from one angle enables better description of the changes in CFTR quality and from another viewpoint builds the persuasive force of atomic testing. Accurately predicting endurance in cystic fibrosis (CF) patients can help determine the optimal timing for lung transplantation (LT) in patients with end-stage respiratory disease. Current recommendations state that if the restricted expiratory volume (FEV1) is less than 30% of theoretical, the patient should undergo her LT test. Although FEV1 certainly plays a role in CF-related death, we expected endurance behavior in CF patients to show significantly more variability. Since it is automated, clinical practitioners might very well use it to build prognostic models without needing a deep understanding of machine learning. Our studies showed that the model developed using Auto Prognosis is more accurate than existing rules and other competing models.