In the realm of healthcare, ensuring medication safety and preventing errors are paramount to improving patient outcomes and minimizing adverse events. Nurses and pharmacists play crucial roles in promoting medication safety through their involvement in various stages of the medication use process. This review article aims to evaluate the specific contributions of nurses and pharmacists in enhancing medication safety and error prevention within healthcare settings. The review will examine the responsibilities of nurses and pharmacists in medication management, including medication reconciliation, drug administration, patient education, and medication monitoring. It will also explore the collaborative efforts between nurses and pharmacists in conducting medication reviews, identifying and resolving medication-related problems, and implementing strategies to prevent medication errors. Furthermore, the article will discuss the impact of interdisciplinary communication and teamwork between nurses and pharmacists on enhancing medication safety practices. Additionally, the review will highlight the importance of ongoing education and training for nurses and pharmacists to enhance their knowledge and skills in medication safety practices. It will also address the role of technology, such as electronic health records and medication management systems, in supporting nurses and pharmacists in their medication safety efforts. Overall, this review article aims to provide a comprehensive overview of the roles of nurses and pharmacists in promoting medication safety and error prevention, emphasizing the significance of their collaboration and the implementation of best practices in healthcare settings.