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ISSN 2063-5346
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EVALUATION OF ANTI-DIABETIC ACTIVITY OF ISOLATED FRACTIONS OF CINNAMOMUM ZEYLANICUM

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Dr .P. Pandian1, Dr.A.Madhukar2, Sampath Kumar.Ch1*
» doi: 10.48047/ecb/2022.11.12.111

Abstract

The present study focuses the determination of the anti-diabetic activity of the extracted fractions of Cinnamomum zeylanicum in rats with diabetes induced through STZ. The 20 mg/kg and 40 mg/kg doses of Cinnamomum zeylanicum were given to the rats for 28 days. Using the accu-chek active test meter, blood glucose levels were measured to assess the anti-diabetic effects of the isolated fractions. Additionally, a comparison was made with the standard anti- diabetic medication, Pioglitazone, was given to another group of rats at a normal dose of 2.7 mg/kg. The results revealed that Cinnamomum zeylanicum had significant anti-diabetic activity. Also, the Cinnamomum zeylanicum remained safe till 300 mg/kg in acute toxic and 1000 mg/kg in sub-acute toxic studies and had photochemically. From these findings it can be inferred that Cinnamomum zeylanicum has lowered FBG in experimentally induced diabetic rats.

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