Intro: Workload related workforce concerns in primary care are major motivators for rising global pattern of expanding nurse positions. Advanced nursing staff are progressively being recruited to perform tasks and duties that were formerly performed by doctors. Because the adoption rate of any novel function inside multidisciplinary teams remains complicated and time-consuming, this is essential to recognize elements that can impede or promote enhanced professional nursing part in healthcare settings. Aim: Identifying, assessing, in addition synthesizing the challenges and enablers that influence the deployment of enhanced professional positions in primary care backgrounds. Methods: A scoping research remained undertaken and reported in line to PRISMA-ScR utilizing the Arksey and O'Malley methodology. Two impartial reviewers selected the studies and assessed their methodology. The relevant data were research features, environment, individuals, and information describing the advanced professional nursing role were retrieved using a pre-piloted extraction form. An adapted Lahore Contributory Framework was used for deductive coding of obstacles and enablers. For obstacles or implementors that might not be categorized using pre-defined categories, we employed deductive coding. Process is done through dialogue. Given the volume of evidence, descriptive analysis was tallied into proof tables, and significant results for obstacles and facilitators were brought together inside a narrative description. Results: A total of 6752 possible records were found by systematic searching, 2855 summaries were reviewed, and 124 complete texts were obtained. The criteria were satisfied by 54 research (published in 78 publications). Half of researches (n=29) remained led in Asia (n=31), and 27/56 were qualitative in nature. The innovative professional nursing role was varied, requiring work across the lifespan and with a variety of patient populations. There was, nevertheless, no consensus on the degree of independence or what comprised daily activity. The most commonly stated obstacle and facilitation were team dynamics. Personal considerations, lines of duty, and 'other' variables (such as money) were also commonly mentioned as roadblocks. Individual variables, mentorship and direction, and 'other' elements were identified as facilitators. Conclusion: Building productive connections through extra healthcare professionals also negotiating position remain important to achievement of enhanced registered nurse role deployment. Team agreement on the job and how it fits within the larger team is also required.