The aim of the study was to evaluate the flexural strength of different types of denture base acrylic resin when they were subjected to different curing procedures (Short and long curing procedures). Materials and Methods: In this study, a total of 160 samples were made using high impact and conventional denture base acrylic resin, 80 samples of each. 40 samples of each denture base resin material where subjected to long and short curing cycle. Samples were carefully retrieved after complete cooling and trimmed and polished. Width and thickness of samples were measured using a digital vernier caliper. The flexural strength of the samples was recorded using the three-point bending test device present in universal testing machine. The results obtained were then statistically analyzed using ANOVA and paired t test. Results: It was observed that the flexural strength of high impact denture base material cured using long and short curing cycle had mean value of 86.52 MPa and 81.23MPa respectively. Conventional denture base resin cured using long and short curing cycle had a mean value of 74.03 MPa and 68.02 MPa respectively. Conclusion: it was concluded that the denture base resin material cured using long curing cycle had higher flexural strength then the denture base material cured using short curing cycle. Trevalon HI showed higher flexural strength compared to DPI, when cured using both long and short curing cycle.