Studies conducted now have validated numerous traditional medicinal plant benefits. Unfortunately, the widespread belief that herbal medicines are extremely safe and free of side effects is not just false. This study sought to determine whether a black pomegranate peel ethanolic extract could have unfavorable effects on rats when given to them in a short amount of time. The extract's effects were assessed in a study of a range findings study. The fruits of black pomegranate (Punica granatum L.) were harvested from orchards In Alkhalis city and Abosyda district -Diyala Governorate, Iraq in September 2021. Dried pomegranate peel was extracted by ethanol 70% containing 1% acetic acid. Phytoconstituent analysis of Peel Extract of Black Pomegranate (BPPE) was carried out by Gas chromatography-mass. The safety of BPPE evaluate by a range-finding study, which is conducted on a total of Twenty-five adult female Wistar rats (Swiss albino rats aged 4-8 months with a weight range 150 to 176 grams. Animals were divided equally into four groups and dosed orally BPPE 2g, 3g, 4g, 5g/kg B.W. of BPPE by stainless gastric gavage needle gauge (18G) for seven consecutive days. When there was, no mortality observed after seven days. The additional five female rats were used and dosed with 15g/Kg, B.W. of BPPE at the same protocol that has been used before. The physical properties of BPPE were dark purple, thick and sticky, had a sour taste and aromatic, the yield extract was (54.9%). The Phytoconstituent exhibited an abundance of esters, furans, Phenols, alkaloids, and saturated fatty acids. The outcome range-finding study revealed that BPEE exhibited no toxic signs but interestingly revealed a significant increase in body weight of all experimental groups that received various dosage rates of BPEE. It could be concluded that is BPEE is practically safe to be administered.