The global supply of fossil fuels is finite and is predicted to run out in the next 65 years. The focus has been on clean, renewable, and sustainable nonpetroleum fuels due to the quick depletion of the global crude oil supplies and environmental concerns. Development of conventional fuel for IC engines is necessary due to the energy crisis and environmental damage caused by fossil fuels. There have been several studies done on utilizing Isoamyl Alcohol and Isobutanol as a fuel in SI engines. Current study, effect of Isoamyl alcohol (Isopentanol or 3-methyl 1-butanol) and Isobutanol/gasohol fuel proportions on SIE emission parameters were investigated. The multi-point fuel injection system is more environmentally friendly because it reduces the amount of dangerous chemicals that are released when fuel is burned. Fewer harmful byproducts are produced when fuel burns inside the engine because fuel is delivered to it more precisely. The tools used by the engine to clean the exhaust have been improved through a multi-point system of fine tuning. Therefore, multi-point systems result in cleaner air and an engine. For the purpose of defining emissions, tests were carried out on CRs (11.0:1) at three different engine rpm’s ranging from 2000, 3000, 4000 and 5000 using four different fuel blends (B0, 100% petrol, B10, 90% petrol, 10% Isoamyl alcohol and 10% isobutanol), and B20, 80% petrol, 20% Isoamyl alcohol and 30% isobutanol). According to experiment results, using Isoamyl alcohol reduced exhaust emissions values when compared to using petrol. From the experimental work it is observed that when speed increases all emissions ( CO,CO2,O2,HC & NOX) are also increased against maximum speed of 4500 rpm.