Nurses play a crucial role in the healthcare of individuals with IDD, as they often require specialized care and support to meet their unique needs. By exploring the experiences of nurses in this field, we aim to shed light on the challenges they face, the rewards they experience, and the innovative strategies they use to improve the quality of life for individuals with IDD. The review will synthesize existing literature on the topic, drawing on qualitative and quantitative studies, as well as case reports and expert opinions. We will examine the various aspects of care provision for individuals with IDD, including communication challenges, behavioral management, healthcare coordination, and advocacy. By understanding the experiences of nurses in these areas, we can identify gaps in knowledge and areas for improvement in care delivery. Furthermore, this review will highlight the strategies that nurses employ to enhance the quality of life for individuals with IDD. These strategies may include person-centered care approaches, interdisciplinary collaboration, education and training initiatives, and the use of assistive technologies. By identifying effective strategies, we can help inform best practices in the care of individuals with IDD and improve outcomes for this population. In conclusion, this review aims to provide valuable insights into the experiences of nurses caring for individuals with IDD and the strategies they use to enhance quality of life. By synthesizing existing literature and identifying key themes and strategies, we hope to contribute to the ongoing dialogue on improving care for individuals with IDD and promoting their overall well-being.