This study aimed to investigate the impact of supplementary nourishment on the general health and nutritional status of pediatric patients, with a specific focus on the utilization of dietary supplements for treating pediatric malnutrition. A total of 200 children (aged 5 to 10), all affected by malnutrition, participated in the research. Notably, none of the participants had prior exposure to vitamin B6 supplements. Evaluation parameters included bone density, weight, and height, and statistical analysis was conducted using SPSS. The results revealed a positive response to treatment with vitamin B6 supplements, leading to progressive dose increases to maximize individual benefits. Elevated vitamin levels were indicative of improved absorption and adherence to the treatment plan. Significantly (p<0.005), affected children experienced a substantial increase in both height and weight following the abrupt rise in vitamin levels. Moreover, bone density showed a gradual improvement with oral vitamin supplementation. In conclusion, oral supplementation of vitamin B6 demonstrated favorable effects on the metabolic and nutritional well-being of children. The results suggest that vitamin supplements could serve as a reasonable additional therapy for most malnourished youngsters.