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ISSN 2063-5346
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EXTRACTION, ISOLATION AND EVALUATION OF ANTI-DIABETIC ACTIVITY OF CLITORIA TERNATEA Linn.

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Kishor Danao, Sunder Singh
» doi: 10.53555/ecb/2022.11.12.280

Abstract

Clitoria ternatea, often known as Butterfly pea, is a member of the Fabaceae family. From Clitoria ternatea Linn, several secondary metabolites, such as triterpenoids, flavonol glycosides, anthocyanins, and steroids, were identified. This work aims to assess the preliminary phytochemical screening and anti-diabetic potential of the Clitoria Ternatea bark extract in albino wistar rat models. The extract was concentrated after distillation. In alloxan-induced diabetic rats, the extract was administered orally once at doses of 200 and 400 mg/kg to test for anti-diabetic efficacy. At several time points, including acute and sub-acute, the blood glucose level was measured, and histological analyses were carried out to assess whether cells were regenerating. In both the acute phase (after 5 hours) and the subacute study (after 1 day), dosages of 200 and 400 mg/kg of the extract effectively reduced blood glucose levels in diabetic rats. The histopathological investigation revealed that both extract dosages resulted in greater regeneration of cells.

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