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ISSN 2063-5346
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FABRICATION AND CHARACTERIZATION OF BISOPROLOLFUMRATE ORAL MOUTH DISSOLVING FILM BY SOLVENT CASTING METHOD

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Shubham Mishra, Dr. Anupam Kumar Sachan, Saurabh Singh
» doi: 10.53555/ecb/2023.12.si10.00564

Abstract

Medical professionals and pharmaceutical companies have continuously emphasized patient acceptance of the oral route of administration over the parenteral, topical, rectal, and vaginal routes. Patients have shown interest in this technique because of how simple it is to use and how little it costs. The oral cavity has the potential to be a site for medicine delivery due to its unique environment. Oral solid dose forms like mouth-dissolving films disintegrate and dissolve in the mouth without the use of water. Choking-averse youngsters, elderly people, and those with dysphasia are increasingly embracing the usage of mouth-dissolving films. Weight uniformity of the film was performed and find in an average of 30.9 mg and the thickness was 0.85 mm. The formulation pH was optimum in range. The folding durability was good. The disintegration time of the film was in the range 30-54 second. In-vitro drug release was performed and get in the range of 89.34- 97.17 %.

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