Current study focus on fabrication of a multipurpose model that was used for various pharmacological screenings like: spinal cord injury, exercise in diabetes mellitus, grip strength on rats. Rotarod performance test is based on rotating rod with force motor activity being applied usually by a rat. Functions of test include evaluating balance, grip strength motor co-ordination of the rats especially in testing the effect of experimental drug. 1 The test may be useful as a sensitive indicator of trauma induced by brain injury to laboratory rodents2. The rota rod consists rotating cylinder, which itself is motor driven 3. The speed of the rotating cylinder can be controlled. The newly fabricated was operate in such a way that it will utilise the rotating cylinder of rotarod as one of the roller of treadmill which will help in running the belt at desired speed. This modification can be used in the study of STZ induced diabetic rats that was forced to exercise and the effect of this exercise was monitored. There are already many studies conducted for the effect of STZ induced diabetes Mellitus where it is proven that the treadmill exercise shows significant reduction in the symptoms of said disease. 4