This study presents a novel readout method for cantilever-based biosensors, which has the potential as both a quick and inexpensive "point of care" device and an intriguing research instrument. The cantilever-based micro/nonmanufacturing procedures and associated challenges are described. The expedient's behaviour is analyzed using a COMSOL simulation. An FPGA-based control circuit has been designed to address the complex arrangements of the readout mechanism in the process of encapsulating the instrument. The circuit can compensate for deviations caused by the fabrication process by using electrostatic actuation. The finite element analysis of microcantilever-based biosensing with a feedback-controlled electrical readout mechanism is presented in this study. The resultant deflection concerning voltage and stress is investigated. The feedback control circuit was developed and tested using the Artix-7 FPGA and associated electronic circuitry. As a result, the sensor's dependability challenges are also being studied, and the suggested readout method's performance in design metrics is around 47% greater than typical optical readout methods.