To evaluate the effect of varying orthodontic forces on different orthodontic materials and surrounding dentofacial structures using Finite Element analysis. Materials and methods: CT scan of the patient is converted into digital images with the help of MIMICS 14.0 software. Dimensions of mini-implant screws were obtained using scanned electron microscopy. Mini impalnts, and archwires are constructed using CATIA V5 R19 software. Blue light scanner is used for scanning brackets. Maxillary dentition including, PDL, and surrounding Bone were modelled using MIMICS software's. Brackets, mini-implant screws and archwires are modelled using CATIA software. Meshing of all the models is carried out using ANSYS software. Results: The maximum and minimum stress with different orthodontic materials in the mini-implant screws, surrounding bone, dentition, and PDL were recorded. ANSYS 15.0 software is used to carry out Finite Element Analysis. After applying Loads and Material Properties, solving is done. Conclusion: Application of varying orthodontic force produces maximum stress distribution in various dentofacial structures. While increasing the frequency of forces, there is significant decrease in stress distribution