Celecoxib is BCS class II drug with low solubility and high permeability used in the treatment of pain and inflammation. In the current research Celecoxib was subjected for wet granulation process through High shear granulation process using various excipients. The angle of repose of the CEB blend was good. The loose bulk density, tapped density, Hausner's ratio, Carr’s compressibility index had good flow properties. During post compression thickness, weight variation, hardness, disintegration time and the friability were satisfactory and within limits. The drug content uniformity by HPLC using UV detector at 254 nm was 99.65± 0.48. The finalized F4 formulation shows drug release up to 12th hr 99.3% and the marketed products release hours up to 9th hours 99.6%.