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ISSN 2063-5346
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Formulation and Evaluation of Antifungal Activity of Polyherbal Gel

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Sakshi Singh , Dr. Shaheen Sultana , Dr. Anna Balaji
» doi: 10.48047/ecb/2023.12.si7.383

Abstract

Typically, plants have been used to cure various ailments in accordance with their traditional uses. Throughout the world, the usage of drugs derived from plants is growing in popularity. Thus, the current study's objective was to create a polyherbal gel using aqueous extracts of several plants and assess its antifungal effectiveness.The gel formulation consisted of Argemonemexicana, Terminalia arjuna, and Azadirachtaindica’s aqueous extract. The resulting formulation's antifungal activity was tested using the disc diffusion method on isolated fungi. Additionally, the formulation's appearance, homogeneity, pH, viscosity, and rheological tests, spreadability, and percentage of drug release were all physically evaluated.The created formulation F3 had the highest zone of inhibition among all the prepared formulations, according to stability and physicochemical assessments as well as microbiological testing.Our study led us to the conclusion that these formulations had effective antifungal properties, making them safe for use on human skin.

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