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BIOCHEMISTRY OF FASTING – A REVIEW ON METABOLIC SWITCH AND AUTOPHAGY.
Volume - 13 | Issue-1
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ONE-POT ENVIRONMENT FRIENDLY SYNTHESIS OF IMINE DERIVATIVE OF FURFURAL AND ASSESSMENT OF ITS ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL
Volume - 13 | Issue-1
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MODELING AND ANALYSIS OF MEDIA INFLUENCE OF INFORMATION DIFFUSION ON THE SPREAD OF CORONA VIRUS PANDEMIC DISEASE (COVID-19)
Volume - 13 | Issue-1
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INCIDENCE OF HISTOPATHOLOGICAL FINDINGS IN APPENDECTOMY SPECIMENS IN A TERTIARY CARE HOSPITAL IN TWO-YEAR TIME
Volume - 13 | Issue-1
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SEVERITY OF URINARY TRACT INFECTION SYMPTOMS AND THE ANTIBIOTIC RESISTANCE IN A TERTIARY CARE CENTRE IN PAKISTAN
Volume - 13 | Issue-1
Formulation and Evaluation of Dolutegravir and Rilpivirine Tablets: A Factorial Study Incorporating Cyclodextrins and Tween 80
Main Article Content
Abstract
The study aimed to investigate the formulation and evaluation of Dolutegravir and Rilpivirine tablets by incorporating cyclodextrins (β-CD and HPβ-CD) and Tween 80. A factorial design was employed to assess the effects of these excipients on various tablet properties. The results revealed that the inclusion of cyclodextrins and Tween 80 had a significant impact on the characteristics of the tablets. In terms of drug content, the tablets formulated with Dolutegravir and HPβ-CD showed the highest values, with an average of 100.2 mg per tablet. Similarly, the tablets formulated with Rilpivirine and β-CD demonstrated a high drug content of 99.4 mg per tablet.
Article Details
