Ayurveda is a rich source of vast information on therapeutic potentials of numerous herbs. Many simple to complex formulations can be prepared by using the therapeutic attributes of these herbs. Therefore, in the work, an attempt has been made to initiate the manufacturing of Ayurveda hand sanitizers based of various Ayurvedic medicated drugs mentioned in Samhitas, as developing countries such as India are facing a shortage of hand sanitizers which is must prevent the spread Covid-19.