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ISSN 2063-5346
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FORMULATION AND EVALUATION OF RIVAROXABAN BUCCAL TABLETS

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Ranjana G.C,Arti Kori,Dr. Shivanand Patil
» doi: 10.48047/ecb/2022.12.10.634

Abstract

This study aims to explore the potential of tablets in enhancing the buccal delivery of rivaroxaban. Materials and Methods: Buccal tablets formulations of rivaroxaban were prepared using different concentrations of Carbopol-934 as a polymer.Hydroxypropyl methyl cellulose is used as adhision for the preparation of buccal tablets. Microcrystalline cellulose 200, Aerosil, Talcum and magnesium stearate were also used in the formulation. The formulated buccal tablet was evaluated by different parameters such weight variation, hardness, dimension, friability, dissolution, swelling index, drug content and compatibility study.

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