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ISSN 2063-5346
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FORMULATION, DEVELOPMENT AND EVALUATION OF NOVEL FILM FORMING SPRAY: CITRONELLA LEAVES

Main Article Content

Dr. Swati N. Deshmukh, Vanita Gade, Dr. Rajendra Bhambar, Sunita Shewalkar, Payal Pansare, Abhay Jain
» doi: 10.31838/ecb/2023.12.s3.574

Abstract

The intent of this study was to develop a topical citronella oil film-forming spray that could enhance the healing process of wounds. Film-forming sprays have a number of benefits over conventional topical preparations, including consistent medication distribution and dose, improved bioavailability, reduced risk of irritation, continuous drug release, and faster wound healing through moisture control. Polymers and excipients employed in film-forming sprays contribute to improved preparation qualities and active ingredient stability. Different excipient and polymer combinations will produce films with varying properties. Therefore, it is necessary to look at the various categories of polymers and excipients, as well as their assessment criteria, in order to create a film-forming spray that is more effective. The chosen literature comprised studies on the development and assessment of film-forming sprays with potential medical applications that use plasticizers and polymers as film-forming matrices. This article contains the various polymer and excipient types and its concentrations, spraying type, assessments, and crucial variables in determining the spray ability and film characteristics. The review comes to the conclusion that the developed film-forming spray formulation was clear, grittiness free in appearance. The evaluation investigations revealed that the PH becomes similar to that of normal skin and has ability to evaporate swiftly resulting in lesser skin irritation when sprayed on wounds. Spray is more convenient to use, can be applied easily thus improve patient acceptance and compliance.

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