Background: The primary aim of this systematic review is to report on the results of using Zygomatic Implants (ZIs) with the sinus-slot technique in the treatment of upper jaw atrophy. Findings: The search for relevant studies was conducted on PubMed, Google Scholar, and the Cochrane Library databases, as well as through manual searches, with consideration given to language and study period. The use of ZIs was included in any type of clinical trial or series. The search strategy employed Boolean operators "AND" and "OR" for PubMed searches, and "+" and "-" for Google Scholar searches. The search was limited to English language, full text, and human studies, while literature reviews and clinical case reports were excluded. After examining the full text of 61 potential reports, six studies with a total of 166 participants and 276 zygomatic implants were included, with a study period ranging from January 1998 to December 2021, and a follow-up period ranging from 12 to 144 months