Heterocyclic compounds are basically cyclic compounds which are also called as ring structural compounds. These compounds contain ring with carbon and atoms of atleast two different or more than two elements. Compound may also include oxygen, nitrogen, and sulphur. Heterocyclic is one of the major branches of chemistry mainly organic chemistry. Which deals with the synthesis properties of their heterocycles. Some or all the atoms in their molecules are joined in ring, The most common cycles contain five or six atoms. Some are 3- membered, 4 membered, 5 membered, 6membered heterocyclic compounds. Some are condensed or fused heterocyclic compounds. As per their primary classification they are saturated and unsaturated in nature. These heterocycle compounds include many of the biochemical material essential for life. The best known of the simple heterocyclic 5 compound include Pyridine, Pyrrole, Furan, and thiophene. In this present paper we will focus on the structure synthesis, role properties and application of fused on the structure synthesis role properties and application of fused pyridine compound and its advances in anti-inflammatory.