Gastropod from the Babura river were taken by hand and an eckman grab. There were 6 research station, (I) in upstream areas, (II) after plantation areas, (III) after pig farm, (IV) after sand mining, (V) after settlements, and (VI) in downstream areas, sampling from March 2017 to January 2018. Gastropod samples were sent for identification to LIPI Cibinong so that the results obtained were more accurate. Diversity, similarity and dominance index of the gastropod spesies were determined. Data were sratistically verified by PCA using SAS 9.1.3 package. Gastropod community in the river consisted of : 6 genera, namely, (1) Pomacea, (2) Filopaludina, (3) Lymnaea, (4) Terebia, (5) Melanoides, (6) Thiara and 1 sub-genera, namely Clea (Anentome). Diversity at station 4 is low and at stations 2, 5, and 6 is moderate. Similirity at stations 3 to 6 is high. The dominance at stations 3, 5, and 6 is low and at station 4 is medium. Parameters that greatly affect the presence of each species of gastropods in the Babura River are: Pomacea canaliculata by DO, Thiara scraba by current flow, Tarebia granifera by BOD, Melanoides tuberculata by pH, Lymneae rubiginosa by current flow, Filopaludina javanica by temperature, and Clea (Anentome)helena by current flow. The gastropods markers in the Babura river are Lymnaea rubiginosa and Clea (Anentome) helena