The several synthetically produced organic substances like fertilizer, herbicides, medications, and antibiotics has increased the quality of life for people, but also leave behind some harmful effects directly in the air, ground, and the agriculture and ultimately result in environmental pollution. Green chemistry was first recognized in the 19th century. The pharmaceutical and organic sectors are drawn to green chemistry and have adopted it. Green Chemistry was founded with the goals of reducing waste, consuming less energy, utilizing renewable resources, and creating biodegradable substances. It is non-polluting, repeatable, and safe for the environment. The various chemical-related disasters caused by toxicity (being carcinogenic or explosive), physical hazards (being flammable or explosive), and global dangers, were studied in the green chemistry. (Climate change or stratospheric ozone depletion). The guiding concepts of green chemistry can be divided into two categories: "Reducing Risk" and "Minimizing the Environmental Footprint." This specific review provides a concise summary of recent advancements and applications of green chemistry principles to everyday activities, chemical processes, economics, pharmacy practices, and analytical chemistry to create novel medicine molecules.