Since the introduction of Helicobacter Pylori (H. Pylori) to the medical community by Marshall and Warren almost twenty years ago, H. Pylori has always been the focus for clinical research and findings. More than 50% of world’s population is colonized by H. Pylori, with infection more prevalent in developing countries. Unless treated, colonization usually persists lifelong. The infection with H. pylori is responsible for the etiology of various gastrointestinal diseases, like chronic active gastritis without clinical symptoms to peptic ulceration and gastric mucosaassociated lymphoid tissue lymphoma