Geriatric individuals often present with higher prevalence of chronic illness, disability and dependency along with coexisting ailments, which requires the concurrent use of three or more drugs. This may sometimes lead toPIM (potentially inappropriate medication) use. The objectives were to identify the prevalence of PIMs use using the Beers Criteria, 2019 in geriatric population and to observe various factors associated with PIM use. This single center, prospective observational study was conducted at the in-patient departments of Gandhi Hospital, Hyderabad for 6 months in older adults aged equal to > 65 years. The research was initiated after approval from the Institutional Ethics Committee, CMR College of Pharmacy, Hyderabad. A descriptive analysis was performed. Results with a p-value lower than 0.05 were considered statistically significantto describe and identify potential predictors of PIMs use. SPSS version 22 was used for data analysis. Out of 134 collected cases, prevalence of PIMs use was reported in 75 cases, 55.97%. As per Beers Criteria, maximum number of PIMs of 75 cases, 64.1% belonged to category 3. PIMs use was observed more with pantoprazole 26 cases, 22.2%. In 88 cases, 65.6% of patients received more than 5 medications leading to polypharmacy. A p<0.00001 showed polypharmacy association with PIMs use. The various disease conditions prevalent among geriatrics which led to PIMs