Heavy metal contamination has become a growing concern worldwide due to its detrimental effects on human health. This paper aims to provide a comprehensive review of the impact of heavy metal contamination on human health. The paper begins by discussing the bioaccumulation, toxicity, sources, and pathways through which heavy metals enter the human body, including industrial activities, agricultural practices, and environmental pollution. It highlights common heavy metals of concern, such as lead, mercury, cadmium, arsenic, and chromium, outlining their sources, distribution, and toxicological properties.