Background: Saudi Arabia is currently passing through a transformational phase. There is a huge demand on the Saudi healthcare system to provide better healthcare facilities to the rapidly increasing Saudi population, as well as the growing elderly population. The management of human resources in healthcare institution is essential to enable the delivery of efficient and effective medical services and to achieve patient satisfaction. This study aims to investigate the impact of practicing human resources management on the quality of healthcare service and achieving patients’ satisfaction. Lack of trained healthcare professionals and heavy reliance on foreign workers are significant aspects for policymakers to consider and deal with. It is also important to re-examine the healthcare Human Resource Development (HRD) initiatives so as to provide a huge reserve of healthcare professionals with appropriate learning and competence. Although Saudi is the largest Middle Eastern state and is the world’s largest oil producer, the motivation to implementing quality of health care sector human resources performance, the employee retention rate, and the presence of females in the workplace are low in the country. This problem has resulted in low of implementing quality of health care sector human resources performance design quality, construction delays, and end-user dissatisfaction. Aim of the study: To investigate the impact of Implementing Quality of Health Care Sector Human Resources Performance and achieving patients’ satisfaction in Saudi Arabian 2022. Method: cross-sectional, descriptive methodology study to investigate the impact of implementing quality of health care sector human resources Performance and achieving patients’ satisfaction. The study was conducted at Health Care Sector in the Saudi Arabian. Total of 300 eligible participant participated in this study. Results: show the remaining socio-demographic characteristics of the participant, regarding age most of participants 24-35 were (42.0%) the gender majority of participants were(66.0%) were female the employment status majority of participants governmental health sector employee were (59.0%) the experience most of participant from 6-10 years were (42.0%) Conclusion . The management of human resources is essential to enable the delivery of efficient and effective medical services and to achieve patient satisfaction that human resources management has a strong impact on healthcare quality, and most of literatures show the importance of human resources management to achieve the goals of health organizations.