An infection that is connected with medical care is a significant contributor to both morbidity and mortality. One of the most effective preventative measures is practicing proper hand hygiene. The purpose of this article is to provide a summary of recent research that demonstrate the value of multidisciplinary hand-hygiene promotion programs and the possible role that alcohol-based hand rubs could play in enhancing techniques for hand hygiene. It is possible to increase the compliance of health care professionals with regard to HH by providing them with information, education, and communication while also monitoring them continuously.