Background: Hospital administration is a critical component in healthcare systems worldwide, with a primary focus on managing hospital operations to ensure effective healthcare delivery. The evolution of hospital administration has expanded its scope to include patient-centered care, data-driven decision-making, and strategic planning to improve patient outcomes. Positive patient outcomes are essential indicators of healthcare effectiveness, encompassing factors like patient health, satisfaction, recovery, and prevention of adverse events. Objective: This review aims to identify factors contributing to patient outcomes in hospitals, evaluate current administration practices' impact on outcomes, develop strategies for enhancing communication and collaboration among healthcare teams, implement evidence-based practices for improved care and safety, and measure the effectiveness of administrative changes on patient outcomes. Conclusion: Effective hospital administration, characterized by strong leadership, governance structures, ethical decision-making, sound financial management, strategic human resource planning, and a focus on quality improvement and patient safety, plays a crucial role in achieving positive patient outcomes. Strategies such as patient-centered care, interdisciplinary collaboration, effective communication, and team-based healthcare are key in enhancing patient satisfaction and engagement, leading to improved overall patient outcomes. By prioritizing these components, hospital administrators can drive continuous improvement in healthcare delivery and patient well-being, ultimately advancing the quality of care provided in healthcare institutions.