Background: Holistic care, an approach that considers the patient as a whole encompassing body, mind, and spirit, has gained recognition for its positive impact on patient well-being and outcomes. The integration of holistic principles in healthcare settings has been linked to improved patient understanding, self-care, and quality of life. However, there is a gap in understanding and implementation of holistic care among healthcare professionals, particularly nurses. The advent of information and communication technologies (ICT) in healthcare, including Health Information Systems (HIS) and Electronic Medical Records (EMR), has revolutionized healthcare delivery, emphasizing the importance of integrated and collaborative care systems. The incorporation of oral health services into holistic care systems is also crucial in addressing systemic and oral health complications and promoting overall well-being. Objective: This review aimed to investigate the role of different healthcare specialties in holistic care approaches and their impact on patient outcomes. Specifically, the roles of dental technicians, Health Administration specialists, health informatics technicians, specialist nurses, x-ray technicians, and medical record technicians in implementing holistic care approaches are explored. Conclusion: The findings underscore the significance of holistic care in healthcare, emphasizing the pivotal role of healthcare specialists in delivering patient-centered and comprehensive care. By embracing holistic care principles, healthcare professionals can enhance patient outcomes, promote patient empowerment, and improve overall well-being. The integration of holistic care approaches not only benefits patients by addressing various aspects of their health but also enhances the quality and effectiveness of healthcare delivery, ultimately fostering healing and wellness across multiple dimensions.