Introduction: Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by prolonged hyperglycaemia that leads to long-term health consequences.Currently, close to 500 million people are estimated to be suffering from diabetes mellitus (DM), with a predicted startling increase in the upcoming years.Curcumin, the active ingredient of the Curcuma longa plant, has received great attention over the past two decades as an antioxidant, anti-inflammatory, anti-diabetic anticancer agent.cinnamon has been used as a spice and as traditional herbal medicine for anti-inflammatory, antimicrobial, antioxidant, antitumor, cardiovascular, cholesterol-lowering, and immunomodulatory effects Objectives: This currentresearch aims to formulate Some Novel Herbal Composition (Transdermal patch) using Curcumin and Cinnamon Extracts, Various evaluation parameters of transdermal patches like Weight variation test, Folding endurance, Thickness, Drug content study, Drug polymer interaction studies,were performedinvitro drug release studies were performed by using Franz diffusion cell. In vivo studies were performed by using Wistar albino ratsby inducing the diabetics using alloxan monohydrate Conclusion:Transdermal patch using curcumin and extracts of cinnamon were successfully prepared suggesting a comparatively suitable option for treatment of diabetics. Based on the results it can be concluded that curcumin and cinnamon exhibited better in vivo performance in rats and further study on higher animals and on clinical research is required.