Biologically active substances derived from natural sources are of interest at the moment since numerous new therapeutic targets for various diseases have been identified. Humans have been exploring the natural world's bounty for many ages in an effort to find cures for every ailment that affects people.The monocotyledonous plants of the Amaryllidaceae family, which includes the genus Hippeastrum, are very useful to the global economy and the pharmaceutical sector.The Amaryllidaceae family, which has over 1100 species in 75 genera, is widely distributed throughout the tropical, subtropical, and warm regions of the world.For centuries, members of the Amaryllidaceae family of plants have been farmed for their decorative value as well as for use in numerous nations and areas as a source of traditional herbal remedies. The plants of Amaryllidaceae family have been grown for ages as ornamental plants and also for folk herbal treatments in many different countries and regions to treat variety of ailments. Hippeastrum puniceum, a parent of many ornamental hybrid plants, is generally a bulbous plant which is harvested from the wild for local use as a medicine. It produces a clump of 4 - 6 grass-like leaves up to 60cm tall from a globose bulb about 5cm in diameter. It is commonly grown as an ornamental in tropical and subtropical gardens, and also as a pot plant in cooler zones. The objective of this study is to investigate medicinal, and in vitro antioxidant activities of bulb of Hippeastrum puniceum and is collected from Kottayam, Kerala. The different pharmacognostical parameters are evaluated as per standard protocols with required modifications. The in vitro antioxidant activity of petroleum, ether, chloroform, ethyl acetate and ethanolic extract of the bulb is assessed against DPPH free radical scavenging assay, and reducing power assay method using standard protocols which proves that the activities of all bulb extracts against DPPH and reducing power assay method are concentration dependent.