Biologically active substances derived from natural sources are of interest at the moment sinc e numerous new therapeutic targets for various diseases have been identified.Humans have be en exploring the natural world's bounty for many ages in an effort to find cures for every ailm ent that affects people.The monocotyledonous plants of the Amaryllidaceae family, which inc ludes the genus Hippeastrum, are very useful to the global economy and the pharmaceutical s ector.The Amaryllidaceae family, which has over 1100 species in 75 genera, is widely distrib uted throughout the tropical, subtropical, and warm regions of the world.For centuries, memb ers of the Amaryllidaceae family of plants have been farmed for their decorative value as well as for use in numerous nations and areas as a source of traditional herbal remedies.The plants of Amaryllidaceae familyhave been grown for ages as ornamental plants and also for folk herbal treatmentsin many different countries and regions to treat variety of ailments. Hippeastrumpuniceum,a parent of many ornamental hybrid plants, is generally a bulbous plant which is harvested from the wild for local use as a medicine.It produces a clump of 4 - 6 grass-like leaves up to 60cm tall from a globose bulb about 5cm in diameter. It is commonly grown as an ornamental in tropical and subtropical gardens, and also as a pot plant in cooler zones. The objective of this study is to investigate medicinal, and in vitro antioxidant activities of bulb of Hippeastrum puniceumand is collected from Kottayam, Kerala. Thedifferent pharmacognostical parameters are evaluated as per standard protocols with required modifications. The invitro antioxidant activity of petroleum, ether, chloroform, ethyl acetate and ethanolic extract of the bulb is assessed against DPPH free radical scavenging assay, and reducing power assay method using standard protocols which proves that the activities of all bulb extracts against DPPHand reducing power assay method are concentration dependent.