Context: Remineralizing agents are significant in reducing the progression of early carious lesions and clinical treatment of the disease since they are non-invasive techniques to treating the lesions. One of the tooth remineralization agents that has been proven in preventing caries is fluoride. However, due to its detrimental effects which may occur due to overexposure to fluoride, a number of firms create tooth health products without fluoride. Cacao, or chocolate, is a substitute that is employed.Theobromine is one of the alkaloid compounds that can be found in cacao (Theobroma cacao). It is said that theobromine can prevent enamel demineralization and can restore the enamel’s lost hardness.