Introduction: Sutures are classified into two types: absorbable sutures and non-absorbable sutures. For any suture to be effective, the tensile strength must be properly restored. This study focuses mainly on two sutures namely, Vicryl and PGA. Quercetin and Quinidine were taken to analyze the effect it has on the above mentioned sutures. The aim of the study is to find the influence of the compounds quercetin and quinidine on absorbable sutures PGA and Vicryl.