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ISSN 2063-5346
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INSULIN SENSITIVITY AND INSULIN RESISTANCE IN PEOPLE WITH AND WITHOUT METABOLIC SYNDROME – A CASE-CONTROL STUDY

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Violeta Hoxha, Adela Haxhiraj, Klodiana Poshi, Agron Ylli
» doi: 10.31838/ecb/2023.12.1.385

Abstract

Metabolic syndrome is a group of risk factors that includes obesity, insulin resistance, hypertension, and dyslipidemia. Insulin resistance is an important part of the syndrome. We present a study for the evaluation of insulin resistance in metabolic syndrome, compared to a control group. The study included 401 apparently healthy individuals, chosen randomly. It is observed that people with metabolic syndrome have hyperinsulinemia in about 60.2% of individuals, and 39.8% of them had normal values. People with metabolic syndrome had higher insulin resistance that the one without the syndrome. In conclusion, metabolic syndrome is a potential for cardio metabolic disorders. Insulin resistance plays a major role in it through various mechanisms. Compared to individuals without metabolic syndrome, people with MS have higher insulinemia and lesser insulin sensitivity with create an ideal environment for metabolic disease to develop.

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