Silica nanoparticles have recently been used to reduce concrete permeability and seepage, and have attracted the attention of many researchers. This study aimed to investigate the effects of using each silica nanoparticle in concrete alone. It was found that the combination of nano-silica and rebars in concrete, and the combination of nano-silica, concrete, and rebars buried in reinforced concrete could affect the compressive strength, permeability, and seepage of concrete. Also, the percentage of any possible mixture to yield an optimal mixture percentage was discussed. Experiments have demonstrated that concrete with silica nanoparticles, used alone and in combination with different percentages of cement content and different water-to-cement ratios in cubic specimens (the British method), had a greater strength compared to conventional concrete (Type I) under compressive strength, permeability, and seepage tests. The findings of this study indicated that concrete with nano-silica increased its compressive strength and showed lower permeability. Although concrete with nano-silica outperformed conventional concrete and concrete with silica fume and the combination of nano-silica and silica fume of an optimal percentage in concrete performed better than when they were used alone. Considering the greasy and hydrophobic properties of silica, the uniform and compressed micro-structure of nano-silica, and the cohesive and microscopic particles of silica fume, if silica was added to this composition, the sizes, the pores inside the concrete, and the capillary force could be decreased, and thus concrete of higher compressive strength and low seepage and permeability could be produced, which would decrease cracks and the corrosion of rebars buried in concrete