Background: This longitudinal psychiatric study delves into intricate connection among early childhood trauma and the development of borderline personality disorder (BPD). BPD is very complicated and debilitating mental health condition considered by pervasive designs of instability in interpersonal relationships, self-image, and affect, and people through the history of early trauma can be at an enlarged danger of developing this disorder. Understanding the nuanced interplay between early adverse experiences and the emergence of BPD is crucial for advancing our knowledge of risk factors and informing targeted interventions. Aim: The primary aim of our current research is to comprehensively examine impact of early childhood trauma on development and progression of borderline personality disorder. By employing a longitudinal approach, we aim to trace the trajectory of BPD symptoms over time and examine the potential moderating and mediating factors that contribute to association among early trauma exposure and the manifestation of BPD. Methods: We will recruit a diverse sample of participants who have experienced early childhood trauma and assess them at regular intervals using standardized psychiatric assessments, interviews, and self-report measures. In addition to collecting data on BPD symptoms, our comprehensive assessment battery will include measures of psychosocial functioning, cognitive processes, and genetic factors. Statistical analyses, including regression modeling and path analysis, will be employed to elucidate the complex pathways linking early trauma to BPD outcomes. Results: The study aims to provide empirical insights into associations among initial childhood trauma and development of Borderline Personality Disorder. By examining a range of variables, including potential protective factors and genetic markers, we anticipate uncovering nuanced patterns and contributing factors that may influence the course of BPD over time. Conclusion: This research has the potential to enhance our understanding of the etiological aspects contributing to development of Borderline Personality Disorder, with a particular focus on the role of early childhood trauma. The findings may inform targeted interventions and preventive strategies for individuals at risk, ultimately improving the quality of life for those affected by BPD.