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Investigation of anxiolytic activity of leaf extracts of Eclipta alba and Ziziphus jujube in animal models

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1Annepaka Eliya Raju, 2Dr. R. Muthulakshmi, 3Dr. P. Sri Lakshmi
» doi: 10.48047/ecb/2022.11.12.011

Abstract

The present study deals with the investigation of alcoholic extracts of the plant Eclipta alba and Ziziphus jujube for anti-anxiety activities in rodents. The alcoholic extracts were administered in alone and in combination with a dose of 250 and 500 mg/kg, p.o. The findings indicated anxiolytic activity of the alcoholic extracts of Ziziphus jujube extracts and its combination when compared with standard and control groups. The results point towards the potential neuropharmacological activity of the plant Eclipta alba and Ziziphus jujube as ananxiolytic. Further neurochemical investigations can unravel the mechanism of action of the plant drug with respect to anti-anxiety activity and help to establish the plant in the armamentarium of anxiolytic agents.

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