About 700 species of Ipomoea are present in tropical and subtropical regions of the world. In this work we mainly focus on Ipomoea cairica species. This plant is found in waste areas, rainforest margins, open woodlands, bush-land, gardens, fences, coastal sand dunes and vegetation growing near water way. It belongs to Convolvulaceae family and this plant is used as food, medicines, and as ornamental plants in religious ritual. In this work we mainly focus on chemical constituents and biological activity of Ipomoea cairica. The extractof I. cairica contains alkaloids, flavonoids, lactone, glycoside, tannins, phenols, amino acid, and tannins. Extraction of plant was done by maceration or soxhlation with methanol, ethanol, chloroform, acetone, pet ether solvent. Ipomoea cairica extract having several medicinal properties such as anti-microbial, anti-cancer, anti-HIV, anti-oxidant, anti-inflammatory, mosquitos’ larvicidal properties and neuroprotective.