The solubility of drugs is a vital factor in dosage form development. When a poorly water-soluble drug has to be incorporatedintoa hydrophilic vehicle, the formulation tends to decrease the bioavailability. Various nanoformulations like nanoparticles (NP), nanosuspensions, nanocapsules, nanospheres, nanogels, nanotubes, etc, are used for improvement in dosage form regarding solubility, absorption, targeted drug delivery, and increase in half-life.Nanoparticles are being used for various drug delivery systems for the betterment of dosage forms as discussed in the current study.The current study has reviewed the problem of solubility of the poorly