Background: Gastric and duodenal ulcer among Pharm.D (IV,V and VI year students), B.Pharm (III & IV year students) and M.Pharm students how much knowledge they have about the complications and treatment of the peptic ulcer disease. So we conducted a Knowledge, Attitude and Practice study about gastric and duodenal ulcer among pharmacy students. With the primary objective to evaluate to compare &assess knowledge, attitude and practice about gastric and duodenal ulcer.Methods: Knowledge, attitude, practice study was conducted for a period for six months. 175 students were enrolled in the study, inclusion criteria: Pharm.D students (4th to 6th) from vistas are included for the study, B Pharmstudents (3rd -4 th) and M.Pharm students from VISTAS are included for the study, Age above 18 included for the study, Both genders are involved in this study. Exclusion criteria: Pharmacy students not from VISTAS are excluded for this study Pharm.D (I,II and III)students, B Pharm (I and II)students are excluded from this study. Students who are not willing to give concern to the study.Results: Students were responders from Pharm.D, B Pharm and M.Pharm. In that Pharm.D and M.Pharm students has more knowledge and B.Pharm need more knowledge about the peptic ulcer disease. Conclusion: According to the findings, the study participants have a good understanding, fair attitude, and practice of gastric and duodenal ulcer. And also this study concludes that there is enough knowledge regarding gastric and duodenal ulcer. Therefore awareness programs such as educational pamphlets and continuing educational seminars may play important roles in increasing pharmacists’ knowledge and therefore improving their performance in the treatment of gastric and duodenal ulcer.