Internationally, there is a growing focus on the role of the non-dental workforce in improving oral health outcomes, particularly for children. Dental caries is the most common chronic disease affecting children. The impact of chronic pain/discomfort related to dental caries on child cognitive development has been documented, with lack of concentration commonly reported. Since children are not seen routinely by the dentist, they are at risk of developing dental disease. Pediatricians and general physicians who see a child from birth are in the best position to identify early dental problems and to educate the parents about the early oral preventive healthcare. Aim: The present study is designed with an objective to gather the data and evaluate the level of knowledge, attitude and practice toward infant oral healthcare among the pediatricians and general physicians. Methodology: All participants gave verbal consent and the consent procedure was approved by the institutional Ethical Committee/Institutional Review Board. The first part of the questionnaire included general information on pediatricians and general physicians: like gender; working environment; and the number of years in practice. In second part of questionnaire, the knowledge of pediatricians and general physicians were assessed by asking them to answer the questions in questionnaire. Result: Results were obtained by using SPSS version 21. It was found that 70% practioners were not aware about treatment needs of deciduous teeth. Conclusion: There is a need to educate everyone by conducting regular health educative programs.