Laboratories play a crucial role in the quality health care delivery and diagnosis of disease. Automation of laboratory instruments brought tremendous transformation in the diagnostic laboratories. Laboratory automation is the result of combined efforts of both medical , engineering fields with a common target of improving patient care. Accuracy of the test results and minimizing the turnaround time (TAT), reducing the errors, improving lab safety are the main goals of laboratory automation. The present review article focused on automation of different processes of the laboratory