Drug supervision aims to protect the public from hazards caused by inappropriate use of drugs and or hazards from drugs that do not meet quality, efficacy, and safety requirements. For this reason, strict and comprehensive supervision by the Food and Drug Administration (BPOM) is required. Hard drugs are one class of drugs whose delivery must be based on a doctor's prescription and delivered by a pharmacist at a pharmaceutical service facility such as a pharmacy. In practice, there are still many sales of hard drugs without a doctor's prescription in pharmacies, so the supervision carried out by BPOM to enforce this regulation needs to be questioned for its effectiveness. This research is a type of empirical legal research. The data obtained from the research were analyzed qualitatively and descriptively to conclude. Data/information is obtained from the results of surveys and interviews with pharmacy owners, pharmacists in charge of pharmacies, and BPOM Gorontalo officers.