Background: Anal fissure is defined as longitudinal tear in lower end of anal canal. In modern science, conservative treatment of acute fissure in Ano includes oral analgesic and laxative along with ointment having anesthetic & healing properties with varied prognosis. Similarly, surgical treatment such as lateral sphincterotomy, dorsal fissurectomy and anal advancement flap is practiced with underlying complications such as recurrence, incontinence is even more agonizing than actual pathology. According to Ayurveda Parikartika can be co-related with Fissure in ano. Bhesaja chikitsa is considered as first line of treatment and deepan, pachan, anuloman drugs are advocated along with local therapies such as Basti and Guda Pichu etc.