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BIOCHEMISTRY OF FASTING – A REVIEW ON METABOLIC SWITCH AND AUTOPHAGY.
Volume - 13 | Issue-1
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ONE-POT ENVIRONMENT FRIENDLY SYNTHESIS OF IMINE DERIVATIVE OF FURFURAL AND ASSESSMENT OF ITS ANTIOXIDANT AND ANTIBACTERIAL POTENTIAL
Volume - 13 | Issue-1
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MODELING AND ANALYSIS OF MEDIA INFLUENCE OF INFORMATION DIFFUSION ON THE SPREAD OF CORONA VIRUS PANDEMIC DISEASE (COVID-19)
Volume - 13 | Issue-1
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INCIDENCE OF HISTOPATHOLOGICAL FINDINGS IN APPENDECTOMY SPECIMENS IN A TERTIARY CARE HOSPITAL IN TWO-YEAR TIME
Volume - 13 | Issue-1
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SEVERITY OF URINARY TRACT INFECTION SYMPTOMS AND THE ANTIBIOTIC RESISTANCE IN A TERTIARY CARE CENTRE IN PAKISTAN
Volume - 13 | Issue-1
Method Development and Validation of Novel Analytical Methods for Daclatasvir in Bulk and Pharmaceutical Formulations Using UPLC Technique
Main Article Content
Abstract
A simple accurate, precise rapid isocratic RP-UPLC method development for the estimation of Daclatasvir in tablet dosage form. The chromatographic system was carried on Acquity BEH C18 (50×3.0mm ×1.7µm id) using mobile phase consisting a mixture of 0.1% Orthophosphoric acid: Acetonitrile(60:40) v/v with detection of 248 nm. The retention time of Daclatasvir was found to be 1.190min. Calibration curve was linear over the concentration range of 50-150 µg/mL of Daclatasvir. The correlation coefficient for peak was found to be 0.9996. All the analytical validation parameters were determined and found in the limit as per ICH guidelines.
Article Details
